Desrazoxane

Desrazoxane Brand names, Desrazoxane Analogs

Desrazoxane Brand Names Mixture

No information avaliable

Desrazoxane Chemical_Formula

C₁₁H₁₆N₄O₄

Desrazoxane RX_link

http://www.rxlist.com/cgi/generic2/dexrazoxane.htm

Desrazoxane fda sheet

Desrazoxane FDA

Desrazoxane msds (material safety sheet)

Desrazoxane MSDS

Desrazoxane Synthesis Reference

No information avaliable

Desrazoxane Molecular Weight

268.269 g/mol

Desrazoxane Melting Point

191 - 197 ^oC

Desrazoxane H₂O Solubility

Sparingly soluble

Desrazoxane State

Solid

Desrazoxane LogP

-2.135

Desrazoxane Dosage Forms

Liquid; Powder for solution

Desrazoxane Indication

For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.

Desrazoxane Pharmacology

Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.

Desrazoxane Absorption

IV administration results in complete bioavailability.

Desrazoxane side effects and Toxicity

Intraperitoneal, mouse LD₁₀ = 500 mg/kg. Intravenous, dog LD₁₀ = 2 gm/kg.

Desrazoxane Patient Information