Dyzoxane

Dyzoxane Brand names, Dyzoxane Analogs

Dyzoxane Brand Names Mixture

No information avaliable

Dyzoxane Chemical_Formula

C₁₁H₁₆N₄O₄

Dyzoxane RX_link

http://www.rxlist.com/cgi/generic2/dexrazoxane.htm

Dyzoxane fda sheet

Dyzoxane FDA

Dyzoxane msds (material safety sheet)

Dyzoxane MSDS

Dyzoxane Synthesis Reference

No information avaliable

Dyzoxane Molecular Weight

268.269 g/mol

Dyzoxane Melting Point

191 - 197 ^oC

Dyzoxane H₂O Solubility

Sparingly soluble

Dyzoxane State

Solid

Dyzoxane LogP

-2.135

Dyzoxane Dosage Forms

Liquid; Powder for solution

Dyzoxane Indication

For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.

Dyzoxane Pharmacology

Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.

Dyzoxane Absorption

IV administration results in complete bioavailability.

Dyzoxane side effects and Toxicity

Intraperitoneal, mouse LD₁₀ = 500 mg/kg. Intravenous, dog LD₁₀ = 2 gm/kg.

Dyzoxane Patient Information