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Clasteon Brand names, Clasteon Analogs

Clasteon Brand Names Mixture

  • No information avaliable

Clasteon Chemical_Formula


Clasteon RX_link

No information avaliable

Clasteon fda sheet

Clasteon msds (material safety sheet)

Clasteon MSDS

Clasteon Synthesis Reference

No information avaliable

Clasteon Molecular Weight

244.892 g/mol

Clasteon Melting Point

250 oC

Clasteon H2O Solubility

395 mg/L

Clasteon State


Clasteon LogP


Clasteon Dosage Forms

Capsules; Solution

Clasteon Indication

For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors.

Clasteon Pharmacology

Clodronate is a first generation (non-nitrogenous) bisphosphonate in the same family as etidronate and tiludronate. Clodronate affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the clodronate that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Clodronate has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia.

Clasteon Absorption

After oral administration, absorption is estimated at 1–3% of the ingested dose because of the low uptake from the gastrointestinal tract.

Clasteon side effects and Toxicity

Decreases in serum calcium following substantial overdosage may be expected in some patients. Signs and symptoms of hypocalcemia also may occur in some of these patients.

Clasteon Patient Information

No information avaliable

Clasteon Organisms Affected

Humans and other mammals