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Ostac Brand names, Ostac Analogs

Ostac Brand Names Mixture

  • No information avaliable

Ostac Chemical_Formula


Ostac RX_link

No information avaliable

Ostac fda sheet

Ostac msds (material safety sheet)

Ostac MSDS

Ostac Synthesis Reference

No information avaliable

Ostac Molecular Weight

244.892 g/mol

Ostac Melting Point

250 oC

Ostac H2O Solubility

395 mg/L

Ostac State


Ostac LogP


Ostac Dosage Forms

Capsules; Solution

Ostac Indication

For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors.

Ostac Pharmacology

Clodronate is a first generation (non-nitrogenous) bisphosphonate in the same family as etidronate and tiludronate. Clodronate affects calcium metabolism and inhibits bone resorption and soft tissue calcification. Of the clodronate that is resorbed (from oral preparation) or infused (for intravenous drugs), about 50% is excreted unchanged by the kidney. The remainder has a very high affinity for bone tissue, and is rapidly absorbed onto the bone surface. Clodronate has been shown to prevent or delay skeletal-related events and decrease bone pain as well as normalize calcium levels in the presence of hypercalcemia.

Ostac Absorption

After oral administration, absorption is estimated at 1–3% of the ingested dose because of the low uptake from the gastrointestinal tract.

Ostac side effects and Toxicity

Decreases in serum calcium following substantial overdosage may be expected in some patients. Signs and symptoms of hypocalcemia also may occur in some of these patients.

Ostac Patient Information

No information avaliable

Ostac Organisms Affected

Humans and other mammals