Cephapirin
Cephapirin Brand names, Cephapirin Analogs
Cephapirin Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cephapirin Chemical_Formula
C17H17N3O6S2
Cephapirin RX_link
No information avaliable
Cephapirin fda sheet
Cephapirin msds (material safety sheet)
Cephapirin Synthesis Reference
No information avaliable
Cephapirin Molecular Weight
423.466 g/mol
Cephapirin Melting Point
No information avaliable
Cephapirin H2O Solubility
1030 mg/L
Cephapirin State
Solid
Cephapirin LogP
-0.251
Cephapirin Dosage Forms
Gel; Suspension
Cephapirin Indication
For treatment of infections caused by susceptible bacteria.
Cephapirin Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cephapirin Absorption
No information avaliable
Cephapirin side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cephapirin Patient Information
No information avaliable
Cephapirin Organisms Affected
Enteric bacteria and other eubacteria
