Cefaprin
Cefaprin Brand names, Cefaprin Analogs
Cefaprin Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefaprin Chemical_Formula
C17H17N3O6S2
Cefaprin RX_link
No information avaliable
Cefaprin fda sheet
Cefaprin msds (material safety sheet)
Cefaprin Synthesis Reference
No information avaliable
Cefaprin Molecular Weight
423.466 g/mol
Cefaprin Melting Point
No information avaliable
Cefaprin H2O Solubility
1030 mg/L
Cefaprin State
Solid
Cefaprin LogP
-0.251
Cefaprin Dosage Forms
Gel; Suspension
Cefaprin Indication
For treatment of infections caused by susceptible bacteria.
Cefaprin Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefaprin Absorption
No information avaliable
Cefaprin side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefaprin Patient Information
No information avaliable
Cefaprin Organisms Affected
Enteric bacteria and other eubacteria
