Cephapirin Sodium
Brand names,
Cephapirin Sodium
Analogs
Cephapirin Sodium
Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cephapirin Sodium
Chemical_Formula
C17H17N3O6S2
Cephapirin Sodium
RX_link
No information avaliable
Cephapirin Sodium
fda sheet
Cephapirin Sodium
msds (material safety sheet)
Cephapirin Sodium
Synthesis Reference
No information avaliable
Cephapirin Sodium
Molecular Weight
423.466 g/mol
Cephapirin Sodium
Melting Point
No information avaliable
Cephapirin Sodium
H2O Solubility
1030 mg/L
Cephapirin Sodium
State
Solid
Cephapirin Sodium
LogP
-0.251
Cephapirin Sodium
Dosage Forms
Gel; Suspension
Cephapirin Sodium
Indication
For treatment of infections caused by susceptible bacteria.
Cephapirin Sodium
Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cephapirin Sodium
Absorption
No information avaliable
Cephapirin Sodium
side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cephapirin Sodium
Patient Information
No information avaliable
Cephapirin Sodium
Organisms Affected
Enteric bacteria and other eubacteria