Cefapirin
Cefapirin Brand names, Cefapirin Analogs
Cefapirin Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefapirin Chemical_Formula
C17H17N3O6S2
Cefapirin RX_link
No information avaliable
Cefapirin fda sheet
Cefapirin msds (material safety sheet)
Cefapirin Synthesis Reference
No information avaliable
Cefapirin Molecular Weight
423.466 g/mol
Cefapirin Melting Point
No information avaliable
Cefapirin H2O Solubility
1030 mg/L
Cefapirin State
Solid
Cefapirin LogP
-0.251
Cefapirin Dosage Forms
Gel; Suspension
Cefapirin Indication
For treatment of infections caused by susceptible bacteria.
Cefapirin Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefapirin Absorption
No information avaliable
Cefapirin side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefapirin Patient Information
No information avaliable
Cefapirin Organisms Affected
Enteric bacteria and other eubacteria
