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Cefapirine [INN-French] en es it fr

Cefapirine [INN-French] Brand names, Cefapirine [INN-French] Analogs

Cefapirine [INN-French] Brand Names Mixture

  • Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
  • Rifater (Isoniazid + Pyrazinamide + Rifampin)

Cefapirine [INN-French] Chemical_Formula

C17H17N3O6S2

Cefapirine [INN-French] RX_link

No information avaliable

Cefapirine [INN-French] fda sheet

Cefapirine [INN-French] msds (material safety sheet)

Cefapirine_[INN-French] MSDS

Cefapirine [INN-French] Synthesis Reference

No information avaliable

Cefapirine [INN-French] Molecular Weight

423.466 g/mol

Cefapirine [INN-French] Melting Point

No information avaliable

Cefapirine [INN-French] H2O Solubility

1030 mg/L

Cefapirine [INN-French] State

Solid

Cefapirine [INN-French] LogP

-0.251

Cefapirine [INN-French] Dosage Forms

Gel; Suspension

Cefapirine [INN-French] Indication

For treatment of infections caused by susceptible bacteria.

Cefapirine [INN-French] Pharmacology

Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.

Cefapirine [INN-French] Absorption

No information avaliable

Cefapirine [INN-French] side effects and Toxicity

Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.

Cefapirine [INN-French] Patient Information

No information avaliable

Cefapirine [INN-French] Organisms Affected

Enteric bacteria and other eubacteria