Cefaprin sodium
Brand names,
Cefaprin sodium
Analogs
Cefaprin sodium
Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefaprin sodium
Chemical_Formula
C17H17N3O6S2
Cefaprin sodium
RX_link
No information avaliable
Cefaprin sodium
fda sheet
Cefaprin sodium
msds (material safety sheet)
Cefaprin sodium
Synthesis Reference
No information avaliable
Cefaprin sodium
Molecular Weight
423.466 g/mol
Cefaprin sodium
Melting Point
No information avaliable
Cefaprin sodium
H2O Solubility
1030 mg/L
Cefaprin sodium
State
Solid
Cefaprin sodium
LogP
-0.251
Cefaprin sodium
Dosage Forms
Gel; Suspension
Cefaprin sodium
Indication
For treatment of infections caused by susceptible bacteria.
Cefaprin sodium
Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefaprin sodium
Absorption
No information avaliable
Cefaprin sodium
side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefaprin sodium
Patient Information
No information avaliable
Cefaprin sodium
Organisms Affected
Enteric bacteria and other eubacteria