Cefatrexyl
Brand names,
Cefatrexyl
Analogs
Cefatrexyl
Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefatrexyl
Chemical_Formula
C17H17N3O6S2
Cefatrexyl
RX_link
No information avaliable
Cefatrexyl
fda sheet
Cefatrexyl
msds (material safety sheet)
Cefatrexyl
Synthesis Reference
No information avaliable
Cefatrexyl
Molecular Weight
423.466 g/mol
Cefatrexyl
Melting Point
No information avaliable
Cefatrexyl
H2O Solubility
1030 mg/L
Cefatrexyl
State
Solid
Cefatrexyl
LogP
-0.251
Cefatrexyl
Dosage Forms
Gel; Suspension
Cefatrexyl
Indication
For treatment of infections caused by susceptible bacteria.
Cefatrexyl
Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefatrexyl
Absorption
No information avaliable
Cefatrexyl
side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefatrexyl
Patient Information
No information avaliable
Cefatrexyl
Organisms Affected
Enteric bacteria and other eubacteria