Cefatrex
Brand names,
Cefatrex
Analogs
Cefatrex
Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefatrex
Chemical_Formula
C17H17N3O6S2
Cefatrex
RX_link
No information avaliable
Cefatrex
fda sheet
Cefatrex
msds (material safety sheet)
Cefatrex
Synthesis Reference
No information avaliable
Cefatrex
Molecular Weight
423.466 g/mol
Cefatrex
Melting Point
No information avaliable
Cefatrex
H2O Solubility
1030 mg/L
Cefatrex
State
Solid
Cefatrex
LogP
-0.251
Cefatrex
Dosage Forms
Gel; Suspension
Cefatrex
Indication
For treatment of infections caused by susceptible bacteria.
Cefatrex
Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefatrex
Absorption
No information avaliable
Cefatrex
side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefatrex
Patient Information
No information avaliable
Cefatrex
Organisms Affected
Enteric bacteria and other eubacteria