Cephapirine
Cephapirine Brand names, Cephapirine Analogs
Cephapirine Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cephapirine Chemical_Formula
C17H17N3O6S2
Cephapirine RX_link
No information avaliable
Cephapirine fda sheet
Cephapirine msds (material safety sheet)
Cephapirine Synthesis Reference
No information avaliable
Cephapirine Molecular Weight
423.466 g/mol
Cephapirine Melting Point
No information avaliable
Cephapirine H2O Solubility
1030 mg/L
Cephapirine State
Solid
Cephapirine LogP
-0.251
Cephapirine Dosage Forms
Gel; Suspension
Cephapirine Indication
For treatment of infections caused by susceptible bacteria.
Cephapirine Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cephapirine Absorption
No information avaliable
Cephapirine side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cephapirine Patient Information
No information avaliable
Cephapirine Organisms Affected
Enteric bacteria and other eubacteria
