Cephalexin (free base)
Cephalexin (free base) Brand names, Cephalexin (free base) Analogs
- Alcephin
- Alexin
- Alsporin
- Biocef
- CEX
- Carnosporin
- Cefa-iskia
- Cefablan
- Cefadal
- Cefadin
- Cefadina
- Cefaleksin
- Cefalessina [DCIT]
- Cefalexin
- Cefalexin (JP14)
- Cefalexin Sodium
- Cefalexina [INN-Spanish]
- Cefalexine [INN-French]
- Cefalexinum [INN-Latin]
- Cefalin
- Cefaloto
- Cefaseptin
- Cefax
- Ceforal
- Cefovit
- Celexin
- Cepastar
- Cepexin
- Cephacillin
- Cephalexin (USP)
- Cephalexin (free base)
- Cephalexin 1-hydrate
- Cephalexin hydrate
- Cephalexin monohydrate
- Cephalexine
- Cephalexinum
- Cephanasten
- Cephaxin
- Cephin
- Cepol
- Ceporex
- Ceporex Forte
- Ceporexin
- Ceporexin-E
- Ceporexine
- Check
- Cophalexin
- Durantel
- Durantel DS
- Ed A-Ceph
- Erocetin
- Factagard
- Felexin
- Fexin
- Ibilex
- Ibrexin
- Inphalex
- Kefalospes
- Keflet
- Keflex
- Kefolan
- Keforal
- Keftab
- Kekrinal
- Kidolex
- L-Keflex
- Lafarine
- Larixin
- Lenocef
- Lexibiotico
- Lonflex
- Lopilexin
- Madlexin
- Mamalexin
- Mamlexin
- Medoxine
- Neokef
- Neolexina
- Novolexin
- Nufex
- Oracef
- Oriphex
- Oroxin
- Ortisporina
- Ospexin
- Palitrex
- Panixine Disperdose
- Pectril
- Pyassan
- Roceph
- Roceph Distab
- Sanaxin
- Sartosona
- Sencephalin
- Sepexin
- Servispor
- Sialexin
- Sinthecillin
- Sporicef
- Sporidex
- Syncl
- Syncle
- Synecl
- Tepaxin
- Tokiolexin
- Uphalexin
- Voxxim
- Winlex
- Zozarine
Cephalexin (free base) Brand Names Mixture
- No information avaliable
Cephalexin (free base) Chemical_Formula
C16H17N3O4S
Cephalexin (free base) RX_link
http://www.rxlist.com/cgi/generic/cephalex.htm
Cephalexin (free base) fda sheet
Cephalexin (free base) msds (material safety sheet)
Cephalexin (free base) Synthesis Reference
R. B. Morin, B. G. Jackson, U.S. Pat. 3,275,626,861 (1966,1970)
Cephalexin (free base) Molecular Weight
347.39 g/mol
Cephalexin (free base) Melting Point
326.8oC
Cephalexin (free base) H2O Solubility
1789 mg/L
Cephalexin (free base) State
Solid
Cephalexin (free base) LogP
0.019
Cephalexin (free base) Dosage Forms
Capsules (containing cephalexin monohydrate equivalent to 250 mg or 500 mg cephalexin); Tablet (containing cephalexin monohydrate equivalent to 250 mg or 500 mg of cephalexin); Suspension
Cephalexin (free base) Indication
For the treatment of respiratory tract infections caused by Streptococcus pneumoniae and Streptococcus pyogenes; otitis media due to Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Moraxella catarrhalis; skin and skin structure infections caused by Staphylococcus aureus and/or Streptococcus pyogenes; bone infections caused by Staphylococcus aureus and/or Proteus mirabilis; genitourinary tract infections, including acute prostatitis, caused by Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae.
Cephalexin (free base) Pharmacology
Cephalexin (also called Cefalexin) is a first generation cephalosporin antibiotic. It is one of the most widely prescribed antibiotics, often used for the treatment of superficial infections that result as complications of minor wounds or lacerations. It is effective against most gram-positive bacteria.
Cephalexin (free base) Absorption
Well absorbed from the gastrointestinal tract
Cephalexin (free base) side effects and Toxicity
Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting. The oral median lethal dose of cephalexin in rats is >5000 mg/kg.
Cephalexin (free base) Patient Information
Patients should be counseled that antibacterial drugs including Keflex should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Keflex is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Keflex or other antibacterial drugs in the future.
Cephalexin (free base) Organisms Affected
Enteric bacteria and other eubacteria
