Cefovit
Brand names,
Cefovit
Analogs
Cefovit
Brand Names Mixture
Cefovit
Chemical_Formula
C16H17N3O4S
Cefovit
RX_link
http://www.rxlist.com/cgi/generic/cephalex.htm
Cefovit
fda sheet
Cefovit
msds (material safety sheet)
Cefovit
Synthesis Reference
R. B. Morin, B. G. Jackson, U.S. Pat. 3,275,626,861 (1966,1970)
Cefovit
Molecular Weight
347.39 g/mol
Cefovit
Melting Point
326.8oC
Cefovit
H2O Solubility
1789 mg/L
Cefovit
State
Solid
Cefovit
LogP
0.019
Cefovit
Dosage Forms
Capsules (containing cephalexin monohydrate equivalent to 250 mg or 500 mg cephalexin); Tablet (containing cephalexin monohydrate equivalent to 250 mg or 500 mg of cephalexin); Suspension
Cefovit
Indication
For the treatment of respiratory tract infections caused by Streptococcus pneumoniae and Streptococcus pyogenes; otitis media due to Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Moraxella catarrhalis; skin and skin structure infections caused by Staphylococcus aureus and/or Streptococcus pyogenes; bone infections caused by Staphylococcus aureus and/or Proteus mirabilis; genitourinary tract infections, including acute prostatitis, caused by Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae.
Cefovit
Pharmacology
Cephalexin (also called Cefalexin) is a first generation cephalosporin antibiotic. It is one of the most widely prescribed antibiotics, often used for the treatment of superficial infections that result as complications of minor wounds or lacerations. It is effective against most gram-positive bacteria.
Cefovit
Absorption
Well absorbed from the gastrointestinal tract
Cefovit
side effects and Toxicity
Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting. The oral median lethal dose of cephalexin in rats is >5000 mg/kg.
Cefovit
Patient Information
Patients should be counseled that antibacterial drugs including Keflex should only be used to treat bacterial
infections. They do not treat viral infections (e.g., the common cold). When Keflex is prescribed to treat a
bacterial infection, patients should be told that although it is common to feel better early in the course of
therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of
therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria
will develop resistance and will not be treatable by Keflex or other antibacterial drugs in the future.
Cefovit
Organisms Affected
Enteric bacteria and other eubacteria