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Amikacin Brand names, Amikacin Analogs

Amikacin Brand Names Mixture

  • No information avaliable

Amikacin Chemical_Formula


Amikacin RX_link

Amikacin fda sheet

Amikacin msds (material safety sheet)

Amikacin MSDS

Amikacin Synthesis Reference

H. Kawaguchi, T. Naito, Ger. pat. 2,234,315; H. Kawaguchi et al., U.S. pat. 3,781,268 (both 1973 to Bristol-Myers)

Amikacin Molecular Weight

585.603 g/mol

Amikacin Melting Point

203-204 oC

Amikacin H2O Solubility

1.85E+005 mg/L

Amikacin State


Amikacin LogP


Amikacin Dosage Forms

IM infusion; IM injection

Amikacin Indication

For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.

Amikacin Pharmacology

Amikacin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.

Amikacin Absorption

Rapidly absorbed after intramuscular administration

Amikacin side effects and Toxicity

No information avaliable

Amikacin Patient Information

Amikacin Organisms Affected

Enteric bacteria and other eubacteria