Alprenolol
Alprenolol Brand names, Alprenolol Analogs
Alprenolol Brand Names Mixture
- No information avaliable
Alprenolol Chemical_Formula
C15H23NO2
Alprenolol RX_link
No information avaliable
Alprenolol fda sheet
Alprenolol msds (material safety sheet)
Alprenolol Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Alprenolol Molecular Weight
249.349 g/mol
Alprenolol Melting Point
107-109 oC
Alprenolol H2O Solubility
547 mg/L
Alprenolol State
Solid
Alprenolol LogP
3.144
Alprenolol Dosage Forms
Tablet
Alprenolol Indication
For the treatment of hypertension, angina, and arrhythmia
Alprenolol Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Alprenolol Absorption
No information avaliable
Alprenolol side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Alprenolol Patient Information
No information avaliable
Alprenolol Organisms Affected
Humans and other mammals
