Alpheprol
Brand names,
Alpheprol
Analogs
Alpheprol
Brand Names Mixture
Alpheprol
Chemical_Formula
C15H23NO2
Alpheprol
RX_link
No information avaliable
Alpheprol
fda sheet
Alpheprol
msds (material safety sheet)
Alpheprol
Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Alpheprol
Molecular Weight
249.349 g/mol
Alpheprol
Melting Point
107-109 oC
Alpheprol
H2O Solubility
547 mg/L
Alpheprol
State
Solid
Alpheprol
LogP
3.144
Alpheprol
Dosage Forms
Tablet
Alpheprol
Indication
For the treatment of hypertension, angina, and arrhythmia
Alpheprol
Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Alpheprol
Absorption
No information avaliable
Alpheprol
side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Alpheprol
Patient Information
No information avaliable
Alpheprol
Organisms Affected
Humans and other mammals