Regletin
Brand names,
Regletin
Analogs
Regletin
Brand Names Mixture
Regletin
Chemical_Formula
C15H23NO2
Regletin
RX_link
No information avaliable
Regletin
fda sheet
Regletin
msds (material safety sheet)
Regletin
Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Regletin
Molecular Weight
249.349 g/mol
Regletin
Melting Point
107-109 oC
Regletin
H2O Solubility
547 mg/L
Regletin
State
Solid
Regletin
LogP
3.144
Regletin
Dosage Forms
Tablet
Regletin
Indication
For the treatment of hypertension, angina, and arrhythmia
Regletin
Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Regletin
Absorption
No information avaliable
Regletin
side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Regletin
Patient Information
No information avaliable
Regletin
Organisms Affected
Humans and other mammals