Apllobal
Apllobal Brand names, Apllobal Analogs
Apllobal Brand Names Mixture
- No information avaliable
Apllobal Chemical_Formula
C15H23NO2
Apllobal RX_link
No information avaliable
Apllobal fda sheet
Apllobal msds (material safety sheet)
Apllobal Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Apllobal Molecular Weight
249.349 g/mol
Apllobal Melting Point
107-109 oC
Apllobal H2O Solubility
547 mg/L
Apllobal State
Solid
Apllobal LogP
3.144
Apllobal Dosage Forms
Tablet
Apllobal Indication
For the treatment of hypertension, angina, and arrhythmia
Apllobal Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Apllobal Absorption
No information avaliable
Apllobal side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Apllobal Patient Information
No information avaliable
Apllobal Organisms Affected
Humans and other mammals
