Aptol Duriles
Aptol Duriles Brand names, Aptol Duriles Analogs
Aptol Duriles Brand Names Mixture
- No information avaliable
Aptol Duriles Chemical_Formula
C15H23NO2
Aptol Duriles RX_link
No information avaliable
Aptol Duriles fda sheet
Aptol Duriles msds (material safety sheet)
Aptol Duriles Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Aptol Duriles Molecular Weight
249.349 g/mol
Aptol Duriles Melting Point
107-109 oC
Aptol Duriles H2O Solubility
547 mg/L
Aptol Duriles State
Solid
Aptol Duriles LogP
3.144
Aptol Duriles Dosage Forms
Tablet
Aptol Duriles Indication
For the treatment of hypertension, angina, and arrhythmia
Aptol Duriles Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Aptol Duriles Absorption
No information avaliable
Aptol Duriles side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Aptol Duriles Patient Information
No information avaliable
Aptol Duriles Organisms Affected
Humans and other mammals
