Yobir
Yobir Brand names, Yobir Analogs
Yobir Brand Names Mixture
- No information avaliable
Yobir Chemical_Formula
C15H23NO2
Yobir RX_link
No information avaliable
Yobir fda sheet
Yobir msds (material safety sheet)
Yobir Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Yobir Molecular Weight
249.349 g/mol
Yobir Melting Point
107-109 oC
Yobir H2O Solubility
547 mg/L
Yobir State
Solid
Yobir LogP
3.144
Yobir Dosage Forms
Tablet
Yobir Indication
For the treatment of hypertension, angina, and arrhythmia
Yobir Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Yobir Absorption
No information avaliable
Yobir side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Yobir Patient Information
No information avaliable
Yobir Organisms Affected
Humans and other mammals
