Aptine
Aptine Brand names, Aptine Analogs
Aptine Brand Names Mixture
- No information avaliable
Aptine Chemical_Formula
C15H23NO2
Aptine RX_link
No information avaliable
Aptine fda sheet
Aptine msds (material safety sheet)
Aptine Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Aptine Molecular Weight
249.349 g/mol
Aptine Melting Point
107-109 oC
Aptine H2O Solubility
547 mg/L
Aptine State
Solid
Aptine LogP
3.144
Aptine Dosage Forms
Tablet
Aptine Indication
For the treatment of hypertension, angina, and arrhythmia
Aptine Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Aptine Absorption
No information avaliable
Aptine side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Aptine Patient Information
No information avaliable
Aptine Organisms Affected
Humans and other mammals
