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Aptine Brand names, Aptine Analogs

Aptine Brand Names Mixture

  • No information avaliable

Aptine Chemical_Formula


Aptine RX_link

No information avaliable

Aptine fda sheet

Aptine msds (material safety sheet)

Aptine Synthesis Reference

Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)

Aptine Molecular Weight

249.349 g/mol

Aptine Melting Point

107-109 oC

Aptine H2O Solubility

547 mg/L

Aptine State


Aptine LogP


Aptine Dosage Forms


Aptine Indication

For the treatment of hypertension, angina, and arrhythmia

Aptine Pharmacology

Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.

Aptine Absorption

No information avaliable

Aptine side effects and Toxicity

LD50=597.0 mg/kg (Orally in rats)

Aptine Patient Information

No information avaliable

Aptine Organisms Affected

Humans and other mammals