Gubernal
Gubernal Brand names, Gubernal Analogs
Gubernal Brand Names Mixture
- No information avaliable
Gubernal Chemical_Formula
C15H23NO2
Gubernal RX_link
No information avaliable
Gubernal fda sheet
Gubernal msds (material safety sheet)
Gubernal Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Gubernal Molecular Weight
249.349 g/mol
Gubernal Melting Point
107-109 oC
Gubernal H2O Solubility
547 mg/L
Gubernal State
Solid
Gubernal LogP
3.144
Gubernal Dosage Forms
Tablet
Gubernal Indication
For the treatment of hypertension, angina, and arrhythmia
Gubernal Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Gubernal Absorption
No information avaliable
Gubernal side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Gubernal Patient Information
No information avaliable
Gubernal Organisms Affected
Humans and other mammals
