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Gubernal Brand names, Gubernal Analogs

Gubernal Brand Names Mixture

  • No information avaliable

Gubernal Chemical_Formula


Gubernal RX_link

No information avaliable

Gubernal fda sheet

Gubernal msds (material safety sheet)

Gubernal Synthesis Reference

Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)

Gubernal Molecular Weight

249.349 g/mol

Gubernal Melting Point

107-109 oC

Gubernal H2O Solubility

547 mg/L

Gubernal State


Gubernal LogP


Gubernal Dosage Forms


Gubernal Indication

For the treatment of hypertension, angina, and arrhythmia

Gubernal Pharmacology

Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.

Gubernal Absorption

No information avaliable

Gubernal side effects and Toxicity

LD50=597.0 mg/kg (Orally in rats)

Gubernal Patient Information

No information avaliable

Gubernal Organisms Affected

Humans and other mammals