Alfeprol
Brand names,
Alfeprol
Analogs
Alfeprol
Brand Names Mixture
Alfeprol
Chemical_Formula
C15H23NO2
Alfeprol
RX_link
No information avaliable
Alfeprol
fda sheet
Alfeprol
msds (material safety sheet)
Alfeprol
Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Alfeprol
Molecular Weight
249.349 g/mol
Alfeprol
Melting Point
107-109 oC
Alfeprol
H2O Solubility
547 mg/L
Alfeprol
State
Solid
Alfeprol
LogP
3.144
Alfeprol
Dosage Forms
Tablet
Alfeprol
Indication
For the treatment of hypertension, angina, and arrhythmia
Alfeprol
Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Alfeprol
Absorption
No information avaliable
Alfeprol
side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Alfeprol
Patient Information
No information avaliable
Alfeprol
Organisms Affected
Humans and other mammals