Acebutolol
Acebutolol Brand names, Acebutolol Analogs
Acebutolol Brand Names Mixture
- No information avaliable
Acebutolol Chemical_Formula
C18H28N2O4
Acebutolol RX_link
http://www.rxlist.com/cgi/generic2/ace.htm
Acebutolol fda sheet
Acebutolol msds (material safety sheet)
Acebutolol Synthesis Reference
No information avaliable
Acebutolol Molecular Weight
336.426 g/mol
Acebutolol Melting Point
119-123 oC
Acebutolol H2O Solubility
259 mg/L
Acebutolol State
Solid
Acebutolol LogP
2.356
Acebutolol Dosage Forms
Tablet; Capsule (200 mg and 400 mg)
Acebutolol Indication
For the management of hypertension and ventricular premature beats in adults.
Acebutolol Pharmacology
Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.
Acebutolol Absorption
Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In
Acebutolol side effects and Toxicity
Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.
Acebutolol Patient Information
Acebutolol Organisms Affected
Humans and other mammals
