Acebutololo
Acebutololo Brand names, Acebutololo Analogs
Acebutololo Brand Names Mixture
- No information avaliable
Acebutololo Chemical_Formula
C18H28N2O4
Acebutololo RX_link
http://www.rxlist.com/cgi/generic2/ace.htm
Acebutololo fda sheet
Acebutololo msds (material safety sheet)
Acebutololo Synthesis Reference
No information avaliable
Acebutololo Molecular Weight
336.426 g/mol
Acebutololo Melting Point
119-123 oC
Acebutololo H2O Solubility
259 mg/L
Acebutololo State
Solid
Acebutololo LogP
2.356
Acebutololo Dosage Forms
Tablet; Capsule (200 mg and 400 mg)
Acebutololo Indication
For the management of hypertension and ventricular premature beats in adults.
Acebutololo Pharmacology
Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.
Acebutololo Absorption
Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In
Acebutololo side effects and Toxicity
Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.
Acebutololo Patient Information
Acebutololo Organisms Affected
Humans and other mammals
