Neptal
Neptal Brand names, Neptal Analogs
Neptal Brand Names Mixture
- No information avaliable
Neptal Chemical_Formula
C18H28N2O4
Neptal RX_link
http://www.rxlist.com/cgi/generic2/ace.htm
Neptal fda sheet
Neptal msds (material safety sheet)
Neptal Synthesis Reference
No information avaliable
Neptal Molecular Weight
336.426 g/mol
Neptal Melting Point
119-123 oC
Neptal H2O Solubility
259 mg/L
Neptal State
Solid
Neptal LogP
2.356
Neptal Dosage Forms
Tablet; Capsule (200 mg and 400 mg)
Neptal Indication
For the management of hypertension and ventricular premature beats in adults.
Neptal Pharmacology
Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.
Neptal Absorption
Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In
Neptal side effects and Toxicity
Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.
Neptal Patient Information
Neptal Organisms Affected
Humans and other mammals
