Acetobutolol
Acetobutolol Brand names, Acetobutolol Analogs
Acetobutolol Brand Names Mixture
- No information avaliable
Acetobutolol Chemical_Formula
C18H28N2O4
Acetobutolol RX_link
http://www.rxlist.com/cgi/generic2/ace.htm
Acetobutolol fda sheet
Acetobutolol msds (material safety sheet)
Acetobutolol Synthesis Reference
No information avaliable
Acetobutolol Molecular Weight
336.426 g/mol
Acetobutolol Melting Point
119-123 oC
Acetobutolol H2O Solubility
259 mg/L
Acetobutolol State
Solid
Acetobutolol LogP
2.356
Acetobutolol Dosage Forms
Tablet; Capsule (200 mg and 400 mg)
Acetobutolol Indication
For the management of hypertension and ventricular premature beats in adults.
Acetobutolol Pharmacology
Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.
Acetobutolol Absorption
Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In
Acetobutolol side effects and Toxicity
Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.
Acetobutolol Patient Information
Acetobutolol Organisms Affected
Humans and other mammals
