Sectral
Sectral Brand names, Sectral Analogs
Sectral Brand Names Mixture
- No information avaliable
Sectral Chemical_Formula
C18H28N2O4
Sectral RX_link
http://www.rxlist.com/cgi/generic2/ace.htm
Sectral fda sheet
Sectral msds (material safety sheet)
Sectral Synthesis Reference
No information avaliable
Sectral Molecular Weight
336.426 g/mol
Sectral Melting Point
119-123 oC
Sectral H2O Solubility
259 mg/L
Sectral State
Solid
Sectral LogP
2.356
Sectral Dosage Forms
Tablet; Capsule (200 mg and 400 mg)
Sectral Indication
For the management of hypertension and ventricular premature beats in adults.
Sectral Pharmacology
Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.
Sectral Absorption
Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In
Sectral side effects and Toxicity
Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.
Sectral Patient Information
Sectral Organisms Affected
Humans and other mammals
