Acebutolol HCL
Acebutolol HCL Brand names, Acebutolol HCL Analogs
Acebutolol HCL Brand Names Mixture
- No information avaliable
Acebutolol HCL Chemical_Formula
C18H28N2O4
Acebutolol HCL RX_link
http://www.rxlist.com/cgi/generic2/ace.htm
Acebutolol HCL fda sheet
Acebutolol HCL msds (material safety sheet)
Acebutolol HCL Synthesis Reference
No information avaliable
Acebutolol HCL Molecular Weight
336.426 g/mol
Acebutolol HCL Melting Point
119-123 oC
Acebutolol HCL H2O Solubility
259 mg/L
Acebutolol HCL State
Solid
Acebutolol HCL LogP
2.356
Acebutolol HCL Dosage Forms
Tablet; Capsule (200 mg and 400 mg)
Acebutolol HCL Indication
For the management of hypertension and ventricular premature beats in adults.
Acebutolol HCL Pharmacology
Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.
Acebutolol HCL Absorption
Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In
Acebutolol HCL side effects and Toxicity
Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.
Acebutolol HCL Patient Information
Acebutolol HCL Organisms Affected
Humans and other mammals
