Mercasolyl
Mercasolyl Brand names, Mercasolyl Analogs
- Basolan
- Danantizol
- Favistan
- Frentirox
- Mercaptazole
- Mercasolyl
- Mercazole
- Mercazolyl
- Merkastan
- Merkazolil
- Metazolo
- Methamazole
- Methiamazole
- Methimazol
- Methylmercaptoimidazole
- Metizol
- Metothyrin
- Metothyrine
- Metotirin
- Propyl-Thyracil
- Strumazol
- Strumazole
- Tapazole
- Tapuzole
- Thacapzol
- Thiamazol
- Thiamazole
- Thimazole
- Thycapsol
- Thycapzol
- Thymidazol
- Thymidazole
- USAF EL-30
Mercasolyl Brand Names Mixture
- No information avaliable
Mercasolyl Chemical_Formula
C4H6N2S
Mercasolyl RX_link
http://www.rxlist.com/cgi/generic3/methim.htm
Mercasolyl fda sheet
Mercasolyl msds (material safety sheet)
Mercasolyl Synthesis Reference
No information avaliable
Mercasolyl Molecular Weight
114.17 g/mol
Mercasolyl Melting Point
146 oC
Mercasolyl H2O Solubility
275 g/L
Mercasolyl State
Solid
Mercasolyl LogP
-0.34
Mercasolyl Dosage Forms
Tablet (5 or 10 mg)
Mercasolyl Indication
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Mercasolyl Pharmacology
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Mercasolyl Absorption
Rapid with an oral bioavailability of 93%.
Mercasolyl side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Mercasolyl Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Mercasolyl Organisms Affected
Humans and other mammals
