Basolan
Basolan Brand names, Basolan Analogs
- Basolan
- Danantizol
- Favistan
- Frentirox
- Mercaptazole
- Mercasolyl
- Mercazole
- Mercazolyl
- Merkastan
- Merkazolil
- Metazolo
- Methamazole
- Methiamazole
- Methimazol
- Methylmercaptoimidazole
- Metizol
- Metothyrin
- Metothyrine
- Metotirin
- Propyl-Thyracil
- Strumazol
- Strumazole
- Tapazole
- Tapuzole
- Thacapzol
- Thiamazol
- Thiamazole
- Thimazole
- Thycapsol
- Thycapzol
- Thymidazol
- Thymidazole
- USAF EL-30
Basolan Brand Names Mixture
- No information avaliable
Basolan Chemical_Formula
C4H6N2S
Basolan RX_link
http://www.rxlist.com/cgi/generic3/methim.htm
Basolan fda sheet
Basolan msds (material safety sheet)
Basolan Synthesis Reference
No information avaliable
Basolan Molecular Weight
114.17 g/mol
Basolan Melting Point
146 oC
Basolan H2O Solubility
275 g/L
Basolan State
Solid
Basolan LogP
-0.34
Basolan Dosage Forms
Tablet (5 or 10 mg)
Basolan Indication
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Basolan Pharmacology
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Basolan Absorption
Rapid with an oral bioavailability of 93%.
Basolan side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Basolan Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Basolan Organisms Affected
Humans and other mammals
