Thiamazol Brand names, Thiamazol Analogs
Thiamazol Brand Names Mixture
Thiamazol fda sheet
Thiamazol msds (material safety sheet)
Thiamazol Synthesis Reference
No information avaliable
Thiamazol Molecular Weight
Thiamazol Melting Point
Thiamazol H2O Solubility
Thiamazol Dosage Forms
Tablet (5 or 10 mg)
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Rapid with an oral bioavailability of 93%.
Thiamazol side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Thiamazol Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Thiamazol Organisms Affected
Humans and other mammals