Favistan
Favistan Brand names, Favistan Analogs
- Basolan
- Danantizol
- Favistan
- Frentirox
- Mercaptazole
- Mercasolyl
- Mercazole
- Mercazolyl
- Merkastan
- Merkazolil
- Metazolo
- Methamazole
- Methiamazole
- Methimazol
- Methylmercaptoimidazole
- Metizol
- Metothyrin
- Metothyrine
- Metotirin
- Propyl-Thyracil
- Strumazol
- Strumazole
- Tapazole
- Tapuzole
- Thacapzol
- Thiamazol
- Thiamazole
- Thimazole
- Thycapsol
- Thycapzol
- Thymidazol
- Thymidazole
- USAF EL-30
Favistan Brand Names Mixture
- No information avaliable
Favistan Chemical_Formula
C4H6N2S
Favistan RX_link
http://www.rxlist.com/cgi/generic3/methim.htm
Favistan fda sheet
Favistan msds (material safety sheet)
Favistan Synthesis Reference
No information avaliable
Favistan Molecular Weight
114.17 g/mol
Favistan Melting Point
146 oC
Favistan H2O Solubility
275 g/L
Favistan State
Solid
Favistan LogP
-0.34
Favistan Dosage Forms
Tablet (5 or 10 mg)
Favistan Indication
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Favistan Pharmacology
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Favistan Absorption
Rapid with an oral bioavailability of 93%.
Favistan side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Favistan Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Favistan Organisms Affected
Humans and other mammals
