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Strumazole
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Strumazole Brand names, Strumazole Analogs

Strumazole Brand Names Mixture

  • No information avaliable

Strumazole Chemical_Formula

C4H6N2S

Strumazole RX_link

http://www.rxlist.com/cgi/generic3/methim.htm

Strumazole fda sheet

Strumazole msds (material safety sheet)

Strumazole MSDS

Strumazole Synthesis Reference

No information avaliable

Strumazole Molecular Weight

114.17 g/mol

Strumazole Melting Point

146 oC

Strumazole H2O Solubility

275 g/L

Strumazole State

Solid

Strumazole LogP

-0.34

Strumazole Dosage Forms

Tablet (5 or 10 mg)

Strumazole Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Strumazole Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Strumazole Absorption

Rapid with an oral bioavailability of 93%.

Strumazole side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Strumazole Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Strumazole Organisms Affected

Humans and other mammals