Thiamazole en es it fr

Category

Thiamazole
add to favotites goo dig stu tec squ mys
fac del pro twi yah mya far


Thiamazole Brand names, Thiamazole Analogs

Thiamazole Brand Names Mixture

  • No information avaliable

Thiamazole Chemical_Formula

C4H6N2S

Thiamazole RX_link

http://www.rxlist.com/cgi/generic3/methim.htm

Thiamazole fda sheet

Thiamazole msds (material safety sheet)

Thiamazole MSDS

Thiamazole Synthesis Reference

No information avaliable

Thiamazole Molecular Weight

114.17 g/mol

Thiamazole Melting Point

146 oC

Thiamazole H2O Solubility

275 g/L

Thiamazole State

Solid

Thiamazole LogP

-0.34

Thiamazole Dosage Forms

Tablet (5 or 10 mg)

Thiamazole Indication

For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.

Thiamazole Pharmacology

Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.

Thiamazole Absorption

Rapid with an oral bioavailability of 93%.

Thiamazole side effects and Toxicity

Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.

Thiamazole Patient Information

Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.

Thiamazole Organisms Affected

Humans and other mammals