Thiamazole Brand names, Thiamazole Analogs
Thiamazole Brand Names Mixture
Thiamazole fda sheet
Thiamazole msds (material safety sheet)
Thiamazole Synthesis Reference
No information avaliable
Thiamazole Molecular Weight
Thiamazole Melting Point
Thiamazole H2O Solubility
Thiamazole Dosage Forms
Tablet (5 or 10 mg)
For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis.
Used in the treatment of hyperthyroidism or an overactive thyroid gland, methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. It may also be used to ameliorate hyperthyroidism in preparation for subtotal thyroidectomy or radioactive iodine therapy.
Rapid with an oral bioavailability of 93%.
Thiamazole side effects and Toxicity
Oral LD50 in rats is 2250 mg/kg. Symptoms of overdose include nausea, vomiting, epigastric distress, headache, fever, joint pain, pruritus, and edema. Aplastic anemia (pancy-topenia) or agranulocytosis may be manifested in hours to days. Less frequent events are hepatitis, nephrotic syndrome, exfoliative dermatitis, neuropathies, and CNS stimulation or depression.
Thiamazole Patient Information
Patients should be instructed to report to their physicians any symptoms of agranulocytosis, such as fever or sore throat.
Thiamazole Organisms Affected
Humans and other mammals