Drolban
Category
Drolban Brand names, Drolban Analogs
Drolban Brand Names Mixture
No information avaliable
Drolban Chemical_Formula
C18H15Cl3N2O
Drolban RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Drolban fda sheet
Drolban msds (material safety sheet)
Drolban Synthesis Reference
No information avaliable
Drolban Molecular Weight
381.683 g/mol
Drolban Melting Point
No information avaliable
Drolban H2O Solubility
No information avaliable
Drolban State
No information avaliable
Drolban LogP
5.401
Drolban Dosage Forms
Topical cream (1%); Suppository
Drolban Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Drolban Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Drolban Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Drolban Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Drolban Patient Information
No information avaliable
Drolban Organisms Affected
Yeast and other fungi
