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Emdisterone Brand names, Emdisterone Analogs

Emdisterone Brand Names Mixture

  • No information avaliable

Emdisterone Chemical_Formula

C18H15Cl3N2O

Emdisterone RX_link

http://www.rxlist.com/cgi/generic3/econazole.htm

Emdisterone fda sheet

Emdisterone FDA

Emdisterone msds (material safety sheet)

Emdisterone Synthesis Reference

No information avaliable

Emdisterone Molecular Weight

381.683 g/mol

Emdisterone Melting Point

No information avaliable

Emdisterone H2O Solubility

No information avaliable

Emdisterone State

No information avaliable

Emdisterone LogP

5.401

Emdisterone Dosage Forms

Topical cream (1%); Suppository

Emdisterone Indication

For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.

Emdisterone Pharmacology

Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

Emdisterone Absorption

After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.

Emdisterone side effects and Toxicity

Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.

Emdisterone Patient Information

No information avaliable

Emdisterone Organisms Affected

Yeast and other fungi