2MDTP en es it fr

2MDTP Brand names, 2MDTP Analogs

2MDTP Brand Names Mixture

  • No information avaliable

2MDTP Chemical_Formula

C18H15Cl3N2O

2MDTP RX_link

http://www.rxlist.com/cgi/generic3/econazole.htm

2MDTP fda sheet

2MDTP FDA

2MDTP msds (material safety sheet)

2MDTP Synthesis Reference

No information avaliable

2MDTP Molecular Weight

381.683 g/mol

2MDTP Melting Point

No information avaliable

2MDTP H2O Solubility

No information avaliable

2MDTP State

No information avaliable

2MDTP LogP

5.401

2MDTP Dosage Forms

Topical cream (1%); Suppository

2MDTP Indication

For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.

2MDTP Pharmacology

Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

2MDTP Absorption

After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.

2MDTP side effects and Toxicity

Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.

2MDTP Patient Information

No information avaliable

2MDTP Organisms Affected

Yeast and other fungi