Masterid
Category
Masterid Brand names, Masterid Analogs
Masterid Brand Names Mixture
No information avaliable
Masterid Chemical_Formula
C18H15Cl3N2O
Masterid RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Masterid fda sheet
Masterid msds (material safety sheet)
Masterid Synthesis Reference
No information avaliable
Masterid Molecular Weight
381.683 g/mol
Masterid Melting Point
No information avaliable
Masterid H2O Solubility
No information avaliable
Masterid State
No information avaliable
Masterid LogP
5.401
Masterid Dosage Forms
Topical cream (1%); Suppository
Masterid Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Masterid Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Masterid Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Masterid Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Masterid Patient Information
No information avaliable
Masterid Organisms Affected
Yeast and other fungi
