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Metholone Brand names, Metholone Analogs

Metholone Brand Names Mixture

  • No information avaliable

Metholone Chemical_Formula

C18H15Cl3N2O

Metholone RX_link

http://www.rxlist.com/cgi/generic3/econazole.htm

Metholone fda sheet

Metholone FDA

Metholone msds (material safety sheet)

Metholone Synthesis Reference

No information avaliable

Metholone Molecular Weight

381.683 g/mol

Metholone Melting Point

No information avaliable

Metholone H2O Solubility

No information avaliable

Metholone State

No information avaliable

Metholone LogP

5.401

Metholone Dosage Forms

Topical cream (1%); Suppository

Metholone Indication

For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.

Metholone Pharmacology

Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

Metholone Absorption

After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.

Metholone side effects and Toxicity

Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.

Metholone Patient Information

No information avaliable

Metholone Organisms Affected

Yeast and other fungi