Medrotestron_propionate
Category
Medrotestron_propionate Brand names, Medrotestron_propionate Analogs
Medrotestron_propionate Brand Names Mixture
No information avaliable
Medrotestron_propionate Chemical_Formula
C18H15Cl3N2O
Medrotestron_propionate RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Medrotestron_propionate fda sheet
Medrotestron_propionate msds (material safety sheet)
Medrotestron_propionate Synthesis Reference
No information avaliable
Medrotestron_propionate Molecular Weight
381.683 g/mol
Medrotestron_propionate Melting Point
No information avaliable
Medrotestron_propionate H2O Solubility
No information avaliable
Medrotestron_propionate State
No information avaliable
Medrotestron_propionate LogP
5.401
Medrotestron_propionate Dosage Forms
Topical cream (1%); Suppository
Medrotestron_propionate Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Medrotestron_propionate Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Medrotestron_propionate Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Medrotestron_propionate Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Medrotestron_propionate Patient Information
No information avaliable
Medrotestron_propionate Organisms Affected
Yeast and other fungi
