Masterone
Category
Masterone Brand names, Masterone Analogs
Masterone Brand Names Mixture
No information avaliable
Masterone Chemical_Formula
C18H15Cl3N2O
Masterone RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
Masterone fda sheet
Masterone msds (material safety sheet)
Masterone Synthesis Reference
No information avaliable
Masterone Molecular Weight
381.683 g/mol
Masterone Melting Point
No information avaliable
Masterone H2O Solubility
No information avaliable
Masterone State
No information avaliable
Masterone LogP
5.401
Masterone Dosage Forms
Topical cream (1%); Suppository
Masterone Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
Masterone Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Masterone Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
Masterone Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
Masterone Patient Information
No information avaliable
Masterone Organisms Affected
Yeast and other fungi
