2M-DHTP
Category
2M-DHTP Brand names, 2M-DHTP Analogs
2M-DHTP Brand Names Mixture
No information avaliable
2M-DHTP Chemical_Formula
C18H15Cl3N2O
2M-DHTP RX_link
http://www.rxlist.com/cgi/generic3/econazole.htm
2M-DHTP fda sheet
2M-DHTP msds (material safety sheet)
2M-DHTP Synthesis Reference
No information avaliable
2M-DHTP Molecular Weight
381.683 g/mol
2M-DHTP Melting Point
No information avaliable
2M-DHTP H2O Solubility
No information avaliable
2M-DHTP State
No information avaliable
2M-DHTP LogP
5.401
2M-DHTP Dosage Forms
Topical cream (1%); Suppository
2M-DHTP Indication
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
2M-DHTP Pharmacology
Econazole is an antifungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). Econazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
2M-DHTP Absorption
After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes.
2M-DHTP Toxicity
Overdosage of econazole in humans has not been reported to date. In mice, rats guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and > 160 mg/kg, respectively.
2M-DHTP Patient Information
No information avaliable
2M-DHTP Organisms Affected
Yeast and other fungi
