Alpha-Methyldopahydrazine
Categoria
Alpha-Methyldopahydrazine Marchi, Alpha-Methyldopahydrazine Analoghi
Alpha-Methyldopahydrazine Marchi miscela
Alpha-Methyldopahydrazine Formula chimica
C10H14N2O4
Alpha-Methyldopahydrazine RX link
http://www.rxlist.com/cgi/generic/sinemet.htm
Alpha-Methyldopahydrazine FDA foglio
Alpha-Methyldopahydrazine DMS (foglio di materiale di sicurezza)
Alpha-Methyldopahydrazine Sintesi di riferimento
Chemerda et al. US Pat. 3,462,536 (1963)
Alpha-Methyldopahydrazine Peso molecolare
226.229 g/mol
Alpha-Methyldopahydrazine Temperatura di fusione
203-205oC
Alpha-Methyldopahydrazine H2O Solubilita
3,8 mg / L
Alpha-Methyldopahydrazine Stato
Solid
Alpha-Methyldopahydrazine LogP
0.494
Alpha-Methyldopahydrazine Forme di dosaggio
Compressa (25 mg)
Alpha-Methyldopahydrazine Indicazione
Per il trattamento dei sintomi del morbo di Parkinson idiopatico (paralisi agitante), post-encefalitiche parkinsonismo
Alpha-Methyldopahydrazine Farmacologia
Carbidopa, un inibitore della decarbossilasi non competitivo, è usato in associazione con levodopa per il trattamento del morbo di Parkinson.
Alpha-Methyldopahydrazine Assorbimento
Rapidamente decarbossilata a dopamina nei tessuti extracerebrali in modo che solo una piccola porzione di una data dose viene trasportato invariato al sistema nervoso centrale.
Alpha-Methyldopahydrazine Tossicita
I sintomi di una tossicità carbidopa includono spasmi muscolari, debolezza, spasmi delle palpebre, nausea, vomito, diarrea, un battito cardiaco irregolare, confusione, agitazione, allucinazioni e perdita di coscienza.
Alpha-Methyldopahydrazine Informazioni paziente
Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Alpha-Methyldopahydrazine Atto interessato organismi
Gli esseri umani e altri mammiferi
