Depix
Categorie
Depix Les marques, Depix Analogs
Depix Les marques melange
Depix Formule chimique
C23H25F3N2OS
Depix RX lien
No information avaliable
Depix FDA fiche
Depix msds (fiche de securite des materiaux)
Depix Synthese de reference
PN Craig, CL Zirkle, le brevet américain. 3.282.930 (1966 à SKF)
Depix Poids moleculaire
434.519 g/mol
Depix Point de fusion
No information avaliable
Depix H2O Solubilite
0.000346 mg / ml
Depix Etat
Solid
Depix LogP
4.694
Depix Formes pharmaceutiques
Tablet; injection IM
Depix Indication
Pour une utilisation dans le traitement de la schizophrénie et la dépression
Depix Pharmacologie
Flupenthixol est un anxiolytique, antidépressive et l'agent stabilisateur de l'humeur. Il inhibe les récepteurs centraux des monoamines, en particulier la dopamine D1 et les récepteurs D2. Par conséquent, il augmente la quantité de sérotonine et de noradrénaline que l'humeur de contrôle et de la pensée, et améliore l'humeur.
Depix Absorption
Assez lente et incomplète après administration orale
Depix Toxicite
DL50 = 300 mk / kg (voie orale chez la souris); DL50 = 791 mg / kg (voie orale chez le rat); DL50 = 87 mk / kg (IV chez la souris); DL50 = 37 mg / kg (IV chez le rat)
Depix Information pour les patients
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Depix Organismes affectes
Les humains et autres mammifères
