Depixol
Brand names,
Depixol
Analogs
Depixol
Brand Names Mixture
Depixol
Chemical_Formula
C23H25F3N2OS
Depixol
RX_link
No information avaliable
Depixol
fda sheet
Depixol
msds (material safety sheet)
Depixol
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Depixol
Molecular Weight
434.519 g/mol
Depixol
Melting Point
No information avaliable
Depixol
H2O Solubility
0.000346 mg/ml
Depixol
State
Solid
Depixol
LogP
4.694
Depixol
Dosage Forms
Tablet; IM injection
Depixol
Indication
For use in the treatment of schizophrenia and depression
Depixol
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Depixol
Absorption
Fairly slow and incomplete after oral administration
Depixol
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Depixol
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Depixol
Organisms Affected
Humans and other mammals