Emergil
Brand names,
Emergil
Analogs
Emergil
Brand Names Mixture
Emergil
Chemical_Formula
C23H25F3N2OS
Emergil
RX_link
No information avaliable
Emergil
fda sheet
Emergil
msds (material safety sheet)
Emergil
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Emergil
Molecular Weight
434.519 g/mol
Emergil
Melting Point
No information avaliable
Emergil
H2O Solubility
0.000346 mg/ml
Emergil
State
Solid
Emergil
LogP
4.694
Emergil
Dosage Forms
Tablet; IM injection
Emergil
Indication
For use in the treatment of schizophrenia and depression
Emergil
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Emergil
Absorption
Fairly slow and incomplete after oral administration
Emergil
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Emergil
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Emergil
Organisms Affected
Humans and other mammals