Fluxanxol
Brand names,
Fluxanxol
Analogs
Fluxanxol
Brand Names Mixture
Fluxanxol
Chemical_Formula
C23H25F3N2OS
Fluxanxol
RX_link
No information avaliable
Fluxanxol
fda sheet
Fluxanxol
msds (material safety sheet)
Fluxanxol
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Fluxanxol
Molecular Weight
434.519 g/mol
Fluxanxol
Melting Point
No information avaliable
Fluxanxol
H2O Solubility
0.000346 mg/ml
Fluxanxol
State
Solid
Fluxanxol
LogP
4.694
Fluxanxol
Dosage Forms
Tablet; IM injection
Fluxanxol
Indication
For use in the treatment of schizophrenia and depression
Fluxanxol
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Fluxanxol
Absorption
Fairly slow and incomplete after oral administration
Fluxanxol
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Fluxanxol
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Fluxanxol
Organisms Affected
Humans and other mammals